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Lou Gehrig’s syndrome: Here are the first symptoms of this disease

articleUseronJuly 21, 2026

1.   💪 Unusual weakness in one arm or leg

They are having difficulties:

Climb stairs?

How to keep an object for a long time?

Should I write a message on a shirt or button it up?

This could be one of the first engine signals.

2.   ⚖️ Loss of balance and frequent falls

Coordination becomes more difficult, especially on uneven terrain.
Some describe a feeling of “weak legs” or a hesitant gait.
3.   🤲 Muscle cramps and twitches

Fasciculations are small, involuntary muscle contractions that are visible under the skin (often in the arms or calves).
They can be frequent and bothersome.

LanguageResources

4.   🔊 Language difficulties

Some patients notice a weaker voice, slurred speech, or difficulty articulating correctly.
This is a typical sign when the affected area involves the facial or neck muscles.

5.   ✍️ Loss of dexterity

It is becoming increasingly difficult for you:

Write

Reach for specific objects

Typing on a keyboard

This may indicate a deterioration of the upper motor neurons.

6.   😞 Excessive muscle fatigue

A common sign is unusual, persistent fatigue, even after light exertion.

7.   👄 Swallowing difficulties

Even in the early stages, swallowing difficulties, a feeling of choking, or food getting stuck in the throat can occur

 

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